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Editor's e-Note
In addition to blocking blood flow, ischemic strokes cause harmful enzymes to become active in the brain areas where blood flow is cut off. If not treated promptly, these enzymes can cause brain damage. A new, noninvasive technique developed by researchers at the University of Missouri School of Medicine and the University of California, San Diego, allows doctors to see these molecular changes in real time. The technique involves tagging peptides with MRI contrast agents so that the peptides light up the brain areas that are affected by enzyme activity. The researchers hope that this real-time view of poststroke brain activity will lead to better stroke treatments. Read all about it in this E-News Exclusive.

— Dave Yeager, editor
e-News Exclusive
New Imaging Technique May Give Physicians Clearer Picture
of Stroke Damage

According to the American Heart Association, ischemic strokes account for nearly 90% of all strokes. They occur when a blocked artery prevents blood from getting to the brain and usually result in long-term disability or death. Now, a team of researchers led by the University of Missouri (MU) School of Medicine has developed a new, real-time method of imaging molecular events after strokes―a finding that may lead to improved care for patients.

“During an ischemic stroke, harmful enzymes called gelatinase become overactive in areas of the brain where blood flow is cut off,” says Zezong Gu, PhD, an associate professor of pathology and anatomical sciences at the MU School of Medicine and lead author of the study. “Overactivation of these enzymes causes brain damage. Our team hypothesized that if we could visualize and track this activity in real time, we could then work on developing a way to block the activity and prevent brain damage from occurring.”

Full story »
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In This e-Newsletter
Worth Repeating
“The strength of your radiology practice depends on the strength of your leadership.”

Cheri Canon, MD, FACR, chair of the program committee for the ACR’s annual meeting, scheduled to take place in Washington, D.C. later this month
Featured Jobs
The nation's top employers and recruiters of radiology professionals advertise in Radiology Today magazine and post their job openings on and the Physician Recruitment Center. Check out the most recent opportunities that have been submitted by employers from across the country!

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CHS, Duty locations in Iraq & Afganistan
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Law Firm, Santa Ana, CA
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Other Imaging News
DBT Effective in Cancer Detection, Callback Reduction
The Perelman School of Medicine at the University of Pennsylvania recently announced the results of a study that found that digital breast tomosynthesis was more effective than traditional mammography over a three-year period in detecting cancer and reducing callbacks.

Imaging Shows Impact of PTSD in Earthquake Survivors
An MRI study recently published in the journal Radiology found that the brain structure of earthquake survivors with posttraumatic stress disorder greatly differed from that of earthquake survivors without the condition, according to a release from RSNA.

Chemical Probe ‘Tags’ Cells for MRI Detection
Researchers at the University of California, San Diego have described a process to “tag” cells for the purpose of MRI detection by using a chemical probe, according to a release from the university.

MRI Helps Predict Preterm Birth
RSNA reports that an MRI of the cervix is more effective than ultrasound in predicting the likelihood of preterm birth.
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