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Editor's e-Note
Have you found yourself wondering lately about what’s new in IR? In this month’s e-News Exclusive, we have a couple of items that will satisfy your curiosity. The first explains a new method for targeting diseased cells. The second details a new wrinkle on a tried-and-true procedure. And, in case you missed it, you can catch up on our September issue.

— Dave Yeager, editor
e-News Exclusive
Interventional News

Gene Therapy via Ultrasound Could Offer New Tool in Fight Against Heart Disease and Cancer

Combining ultrasound energy and microbubbles to poke holes in cells may prove to be a new tool in the fight against cardiovascular disease and cancer, according to researchers from the University of Pittsburgh (Pitt) and University of Pittsburgh Medical Center (UPMC). A study on this gene therapy approach, called sonoporation, appears in the Proceedings of the National Academy of Sciences (PNAS).

“We can use ultrasound energy in combination with small, gas-filled bubbles to selectively open up cells to allow the delivery of therapeutic agents,” says Brandon Helfield, PhD, lead author of the study and a postdoctoral fellow at the Center for Ultrasound Molecular Imaging and Therapeutics at UPMC. “With a focused ultrasound beam, this approach lets us tune this delivery to the precise location of disease while sparing healthy tissue. Our study looks at some of the biophysics at play and helps us get closer to refining this technique as a clinical tool.”

Full story »
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In This e-Newsletter
Worth Repeating
“Radiologists can have ‘hunches’ after a first look at a mammogram. We found that these hunches are based on something real in the images. It’s really striking that in the blink of an eye, an expert can pick up on something about that mammogram that indicates abnormality.”

Jeremy Wolfe, PhD, director of the Visual Attention Laboratory at Brigham and Women’s Hospital, on study results that found that radiologists could identify abnormalities in mammograms at better-than-chance averages after seeing images for one-half second
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