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Editor's e-Note
Because it doesn’t use ionizing radiation and can be delivered noninvasively, focused ultrasound is a tantalizing treatment modality. Although its approved medical uses are limited, many researchers and clinicians expect that it will one day offer numerous treatment possibilities, particularly for brain diseases. This month’s e-News Exclusive takes a look at current efforts to make focused ultrasound more accurate and more accessible.

Does your facility use focused ultrasound for treatment? Let us know on Twitter and/or Facebook.

Enjoy the newsletter.

— Dave Yeager, editor
e-News Exclusive
Advancements in Focused Ultrasound Promise Cost-Effective Brain Treatment

Focused ultrasound, often with MR guidance, has shown promise for treating brain diseases. Currently, it is FDA approved to treat essential tremor, and work is ongoing to expand its range of possibilities. There is hope that focused ultrasound may become more useful for other brain diseases, as well, including cancer. One of the main drawbacks of MR-guided focused ultrasound, however, is that MR is an expensive, time-consuming test. To address this challenge, a group of interdisciplinary researchers at Georgia Institute of Technology (Georgia Tech) are testing the parameters of delivering focused ultrasound to the brain without MR guidance.

The projects, which are sponsored by the National Science Foundation, use ultrasound-based methods to measure the contours and density of the skull and focus ultrasound beams precisely in the brain. Because distances as small as 1 mm are significant in brain anatomy, precise focus is essential. Four different labs are conducting research to improve the process.

The lab of Brooks Lindsey, PhD, an assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, is investigating the effects of bone microstructure, specifically the porosity of the trabecular bone layer, on ultrasound imaging. The lab has recently characterized the effect of skull microstructure and angle of incidence on transcranial ultrasound imaging, including ultrafast plane wave Doppler imaging, which can be used for imaging blood flow in large cerebral arteries in stroke patients.

Full story »
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In This e-Newsletter
Worth Repeating
“Human engineers might also learn from this biological trick. The hardness of ant teeth, for example, increases from about the hardness of plastic to the hardness of aluminum when the zinc is added. While there are much harder engineering materials, they are often more brittle.”

— Robert Schofield, of the University of Oregon, regarding a subatomic analysis of ways zinc is harnessed as a tool in the insect kingdom, as published in Scientific Reports
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